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Glossary of Drug Testing Terms

Adulterated Specimen

A specimen to which a substance is added after it was collected. The intent is to hide the drug present or chemically interfere with the testing process so that the drug cannot be detected. A urine specimen containing a substance that is not a normal constituent or contains an endogenous substance at a concentration that is not normal.

Alternative Specimen Test

Any specimen submitted that is not laboratory based urine. It could be laboratory based hair or oral fluid testing or Point of Collection Test kit (instant drug of abuse testing kit)

Custody and Control Form (CCF)

A drug testing form that is required to be used when collecting and testing a DOT safety-sensitive worker. Other types of CCFs are also used when collecting and testing non-DOT regulated drug tests. A Federal Drug Testing custody and Control Form cannot be used for non-DOT collections.

Confirmatory Test

A test that is used to confirm the presence of a specific drug or metabolite. The second or confirmatory testing method must be gas chromatograph/mass spectrometry (GC/MS) if is it is a DOT test. Most non-regulated drug screens are confirmed using the same method, GC/MS (LC/MS/MS available May 2010).

Dilute Specimen

This is the result of the donor drinking large amounts of a liquid before the urine collection or it could be the result of a natural condition. It is a urine specimen with creatinine and specific gravity that is lower than expected human urine.

 

DOT Test

A urine drug screen performed for Department of Transportation safety-sensitive employees. Testing must be requested on a Federal CCF only.

Initial Drug Screen

An immunoassay test (EIA) that is the first or screening tests for drugs of abuse.

 

Invalid Test Result

 

A urine specimen that contains an unidentified adulterant, an unidentified interfering substance, has an abnormal physical characteristic, or has an endogenous substance at an abnormal concentration that prevents the laboratory from completing the test.

Non-negative specimen

A urine specimen that is reported as adulterated, substituted, positive for drugs, or invalid

Normal Result

A negative laboratory test

POCT Test

A point of collection test or instant testing device for drugs of abuse that provides test result in 5-10 minutes after the test is performed. The test is performed at the point of the collection.

Positive Test Result

A drug test that has been confirmed as positive by GC/MS by the laboratory

SAMHSA

The Substance Abuse and Mental Health Services Administration (SAMHSA) is the governing federal agency that regulates all approved drug testing laboratories as well as all standards in drug testing.

Substituted Specimen

A specimen that is not characteristic of human urine. The substituted specimen could be water, salt water, soda, etc. A specimen with creatinine and specific gravity values that is inconsistent with human urine.

Verified laboratory test

A laboratory test result that has been verified by the MRO.